Axplora expands ADC payloads

CDMO Axplora has opened a GMP workshop at its Le Mans site to make payloads for ADCs. Features include three Hastelloy reactors with a production range of 30-200 L, plus space for a fourth, and a dedicated Hastelloy filter dryer for high-level containment and safety. It can produce batches of up to 1.5 kg.

This is part of the France 2030 programme. Axplora already supplies 40% of the world’s marketed ADCs and 50% of FDA-approved ADCs. Le Mans already has six dedicated ADC workshops: two for clinical payload-linker production, two for commercial payloads and two for bioconjugation.