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oligonucleotides

New lab for CatSci

CatSci has opened a second oligonucleotides laboratory, which it will use “to introduce novel workflows for the rapid production of vast numbers of oligos at a scale optimised for rapid screening”. The company is also transforming its largest laboratory space into a centre of excellence for oligonucleotide development by remodelling it to create efficient working spaces for existing and new capabilities.

A key component of the new labs is a fully-automated synthesiser, optimised to create large pools of candidate sequences (up to 384 per run) in as little as eight hours. Using these workflows, CatSci said that it can reduce the time required for a screening campaign using traditional synthesis techniques from around 2,500 hours by over 95% to 104.

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