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Siegfried opens drug substances R&D centre

Swiss CDMO Siegfried has inaugurated its new global R&D centre for drug substances at its site in Evionnaz. The 4,500 m2 centre houses chemical and analytical facilities, laboratories and advanced technologies including flow chemistry, distillation and process analytics, plus office space. There are workspaces for over 100 and 40 new jobs have been created.

Siegfried to acquire Curia site

Swiss CDMO Siegfried has signed binding agreements with Curia Global for the acquisition of a drug substances site in Grafton, Wisconsin. The deal is expected to close by 1 July, subject to customary closing conditions. No financial details are being disclosed, other than that the acquisition is being financed from existing funds and will not change the company’s outlook for 2024 and mid-term financial targets.

Feature article - Maximising product potential with spray drying

Michael Levis of Siegfried overviews the possibilities of a key pharmaceutical technology

The pharmaceutical and biotechnology industries constantly seek innovative methods to enhance product stability, solubility, bioavailability and ease of use. Within this realm, CDMOs serve as invaluable partners in the development and production of high-quality drug products. Among the array of cutting-edge technologies that have transformed the CDMO industry, spray drying has emerged as a versatile and indispensable tool.

Siegfried breaks ground on R&D centre

Siegfried has broke ground for its new global R&D centre for drug substances at its site in Evionnaz, Switzerland. The company is investing up to €23 million at the facility, which will begin operations in 2024 and host about 100 scientists, working alongside another R&D centre at the main site in Zofingen. The centre will host advanced chemical and analytical facilities and laboratories, offering chemical process R&D and analytical development services for the entire drug substances network, Siegfried said.

Drug product centre opens

Following two years of construction work, CDMO Siegfried has officially opened its new development centre for drug products at its sites in Barberà del Vallès and El Masnou near Barcelona. About 40 specialist scientists will work there.

The centre features laboratories and pilot capacities, including dedicated facilities for highly potent oral solid dosage forms. Siegfried said that the opening also completes the successful integration of the two sites into its network. It originally acquired them from Novartis in 2020.

Siegfried breaks ground at Minden

Siegfried has held a groundbreaking ceremony for the largest construction project in its history. The Swiss CDMO will be investing up to CHF 100 million on a large-scale production facility at Minden, Germany. This will have up to 100 m3 of additional reactor capacity for API production when it is commissioned in 2024.

Siegfried to buy two Novartis sites

Siegfried has agreed to buy two drug product sites near Barcelona, Spain, from Novartis, in a deal expected to close by the end of 2020. Terms were not disclosed but Siegfried said that its sales should surpass CHF 1 billion in 2021, with the drug product operations “achieving the targeted critical size”.

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